An Assessment of the Suitability of the Body and Adult Head Coils for Transmission during Paediatric Magnetic Resonance Imaging
G.R. Cook, M.J. Graves, F.J. Robb, D.J. Lomas
Department of Radiology, University of Cambridge, Cambridge, United Kingdom
General Electric Healthcare Coils, Aurora, Ohio, USA
MRI offers many advantages over other modalities and its lack of ionizing radiation is important for children, but can be limited by the radio-frequency (RF) coils available. This work calculates Specific Absorption Rate (SAR) and homogeneity of the RF transmit field (B1+) when imaging infants in adult coils. Two birdcage-type coils were loaded by a tissue model and their B1+ homogeneities ...
T. Suzuki, C. Holloway, S. Taylor
University College London, London, UK
Manual wheelchair users suffer shoulder pain and injury in the long term because of unconscious overuse. The ‘SENSEWHEEL’, which interposes three identical load cells between pushrim and rear wheel, measures the three components of pushing force Fx, Fy and Fz, and axial torque Tx applied at each load cell. Strain gauges were located on a diaphragm forming one face of the load cell. The ...
N. M. Sundaram, M. Sneha, A. Kandaswamy, R. Nithya
PSG College of Technology, Coimbatore, Tamil Nadu, India
Dr. N.G.P. Institute of Technology, Coimbatore, Tamil Nadu, India
The majority of elderly patients are subjected to hip bone replacement due to dislocation of bone, mechanical failure and infection. The life time of the implant varies from patient to patient depending on their daily physical activity. Once the implant fails, re-operation of hip bone replacement is performed. In United States, there are approximately 18 revision hip replacements performed for ...
Advancing Regulatory Science through Integrative Engineering with COMSOL Multiphysics® Software Modeling
G. Zhang 
 Department of Bioengineering, Institute for Biological Interfaces of Engineering, Clemson University, Clemson, SC, USA
The US Food and Drug Administration (FDA) faces significant challenges in its regulatory approval processes due to a lack of relevant science, and many practices are limited by laws enacted in the previous century . Therefore, in recent years, the FDA has identified the need for advancements in regulatory science and innovation. In a broader sense, advancing regulatory science is not just ...
Numerical Simulations Demonstrate Safe Vitrification and Warming of Embryos Using the Rapid-i™ Device
B.O.J. Johansson, Y.A. Tarakanov, H.J. Lehmann, and S.P. Apell
Department of Applied Physics, Chalmers University of Technology, Gothenburg, Sweden
Vitrolife Sweden AB, Västra Frölunda, Sweden
During cryopreservation of human embryos, ice crystal formation in the embryos or in surrounding media may cause cryodamage to them and can be lethal. A strategy to avoid this is the vitrification procedure when the embryo and the surrounding medium undergo the transition to glassy state rather than a crystalline one during cooling. Similarly, recrystallization in the embryo or the medium must ...
Analysis of Heat Transfer in a Complex Three Dimensional Structure Fabricated by Additive Manufacturing - new
C. Settle, K. Hoshino
Biomedical Engineering Department, University of Connecticut, Storrs, CT, USA
The goal of this study was to create a three dimensionally designed biomedical device with multiple functionalities and analyze its simulated heat transfer. The device would be fabricated through additive manufacturing; specifically electron beam melting (EBM). EBM has a feature size constraint of 1 mm (acceptable for this design) and is only capable of manufacturing titanium alloys ; a ...
N. P. Uth , J. Mueller , B. Smucker , A. Yousefi ,
 Department of Chemical, Paper, and Biomedical Engineering, Miami University, Oxford, OH, USA
 Research Computing Support, Miami University, Oxford, OH, USA
 Department of Statistics, Miami University, Oxford, OH, USA
Introduction: Bone tissue has a limited ability for regeneration; critically sized defects cannot self-heal and require medical intervention. Bone tissue engineering (TE) circumvents this issue by growing replacement bone tissue from the patient’s own cells inside scaffolds. TE scaffolds are porous constructs that act as a support structure during bone regeneration and helps cells attach and ...
Lowering of the Interstitial Fluid Pressure as a Result of Tissue Compliance Changes during High Intensity Focused Ultrasound Exposure: Insights from a Numerical Model
E. Sassaroli, B. O'Neill 
The Methodist Hospital Research Institute, Houston, TX, USA
Interstitial fluid pressure (IFP) is elevated in tumors. Owing to this elevated IFP, the interstitial fluid velocity (IFV) is negligible throughout the tumor but significant near the tumor margin. Any therapeutic strategy that can lower IFP will improve drug convection within the tumor and decrease convection of drugs from the tumor margin. High intensity focused ultrasound (HIFU) has been shown ...
T. O. Bassani , T. Bassani , A. Andriguetto , F. Schneider ,
 Instituto Latino Americano de Pesquisa e Ensino Odontológico - ILAPEO, Curitiba, PR, Brasil
 Universidade Tecnológica Federal do Paraná – UTFPR, Curitiba, PR, Brasil
O presente estudo visou a avaliação, por meio do método dos elementos finitos, das tensões geradas em um arco ortodôntico chamado de Arco de Retração Dupla Chave, também conhecido como DKL. Para isso foram modeladas as geometrias do arco DKL, dos bráquets e das coroas dentais, no software COMSOL Multiphysics®. O modelo criado tem como objetivo a substituição dos métodos tradicionais de ...
Passive and Active Deformation Processes of 3D Fibre-Reinforced Caricatures of Cardiovascular Tissues
A. Di Carlo, P. Nardinocchi, T. Svaton, and L. Teresi
Modelling and Simulation Lab, Università Roma Tre, Roma, Italy
Dept. of Structural & Geotechnical Engineering, Università di Roma La Sapienza, Roma, Italy
Dept. of Mathematics, University of West Bohemia, Pilsen, Czech Republic
In this paper, we present a mathematical model of contractile elastic solids meant to simulate various districts of the cardiovascular system, and based on the concepts of active deformation and embedded muscle fibres. Specifically, here we deal with the modeling of the gross mechanics of the Left Ventricle (LV) which is strictly related to its pump function. As is well known, the effectiveness ...