Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Evaluating Nanogaps in Ag and Au Nanoparticle Clusters for SERS Applications Using COMSOL Multiphysics®

R. Asapu [1], R. Ciocarlan [2], N. Claes [3], N. Blommaerts [1], S. Bals [3], P. Cool [2], S. Denys [1], S. Lenaerts [1], S. W. Verbruggen [1]
[1] Department of Bioscience Engineering, DuEL Research Group, University of Antwerp, Belgium
[2] Department of Chemistry, PLASMANT Research Group, University of Antwerp, Belgium
[3] Department of Physics, EMAT Research Group, University of Antwerp, Belgium

Silver and gold nanoparticles are widely used in the field of surface enhanced raman spectroscopy (SERS) because of the unique plasmonic properties. Plasmons or surface plasmon resonance result from the wavelength dependent dielectric properties of noble metals like Ag, Au, Pt etc., which give rise to enhanced near-electric field which is the primary reason for enhancement of Raman signal in ...

3-D Finite Element Modeling of Brain Edema: Initial Studies on Intracranial Pressure Using COMSOL Multiphysics®

X.G. Li[1], H. von Holst[1][2], J. Ho[1], and S. Kleiven[1]

[1]Division of Neuronic Engineering, KTH, Stockholm, Sweden
[2]Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden

Brain edema is one of the most common consequences of serious traumatic brain injuries which is usually accompanied with increased Intracranial Pressure (ICP) due to water content increment. A three dimensional finite element model of brain edema is used to study intracranial pressure in this paper. Three different boundary conditions at the end of Cerebral Spinal Fluid (CSF) were used to ...

Biosimulation of Normal Pressure Hydrocephalus Using COMSOL Multiphysics®

K. Shahim[1], J-M. Drezet[1], J-F. Molinari[2], S. Momjian[3], and R. Sinkus[4]

[1]LSMX, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
[2]LSMS, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
[3]University Hospitals of Geneva and University of Geneva, Switzerland
[4]Waves and Acoustics Laboratory, ESPCI, Paris, France

A numerical finite element model of one human brain is built in COMSOL in order to study a particular form of hydrocephalus, the so called Normal Pressure Hydrocephalus (NPH). The geometry of the ventricles and the skull is obtained by Magnetic Resonance Imaging (MRI) and imported in COMSOL Multiphysics. Form the mechanical point of view, the brain parenchyma is modeled as a porous medium fully ...

Transport of Vocs through Bioflim in Biotrickling Filters

Balasubramanian P[1]
[1]Indian Institute of Technology Madras, Chennai, Tamil Nadu, India

Realising the interlinkage of nature and engineering are of paramount essential while comprehending the basics of system’s performances. Application of biotechniques in air pollution control is one such emerging scientific area, where the understandings of these complex systems demand more utilisation of computing softwares. Recently, biofiltration is a versatile biological air pollution control ...

Understanding the Role of Nanomaterials in DNA Biosensors Through Finite Element Analysis

J. C. Kumaradas[1], A. Zhang[2], Y. D. Davletshin[1]
[1]Ryerson University, Toronto, ON, Canada
[2]University of Waterloo, Waterloo, ON, Canada

Tremendous progress is being made in the integration of nanoparticles into micro-analytical systems for biosensing. These materials are shown to enhance the analyte capture capability of biosensing platforms. We have implemented a computational model that considers the sensor’s geometry, size, analyte concentration and type to predict the number of nucleic acid molecules captured by ...

Transport and Concentration of Charged Molecules in a Lipid Membrane - new

S. D. Evans[1], J. S. Roth[1], M. R. Cheetham[1]
[1]University of Leeds, Leeds, UK

Brownian ratchets and electric fields are used for the transport of membrane components. Transport is achieved through the combination of a pattern with free diffusion. We show a good agreement between simulation and experiment, therefore allowing for further optimisation of the ratchets using COMSOL Multiphysics. In addition to the transport device we also introduce the possibility to ...

Simulation and Experimental Analysis of Drug Release Rates from Magnetic Nanocomposite Spheres - new

L. Saeeednia[1], H. Mehraein[2], F. Abedin[1], K. Cluff[2], R. Asmatulu[1]
[1]Department of Mechanical Engineering, Wichita State University, Wichita, KS, USA
[2]Department of Bioengineering, Wichita State University, Wichita, KS, USA

Targeted drug delivery systems have been wildly studied in cancer therapy due to the toxicity of most of chemotherapeutic drugs. Nanoparticles can be attached to the small molecules of the drugs and serve as drug carriers to deliver the drug molecules into the area of interest. In this research, polymeric microspheres containing biodegradable poly(D, L-lactide-co-glycolide) (PLGA), magnetic ...

Numerical Analysis on Plasmonic Nano-Cucumber Achieving Large EFs and Wide Tuneability of the Peak

A. Zare [1], E. Cutler [1], H. Cho [1],
[1] Center for Biomedical Engineering & Science, University of North Carolina - Charlotte, Charlotte, NC, USA

INTRODUCTION: Researchers in the biomedical field have recently become interested in the potential applications of plasomics. Surface plasmon resonance based on optical properties of metallic nanostructures can be used for detection of special biological targets. Gold nanostructures with different shapes and sizes have been designed to achieve high enhancement factor (EF), wide range of ...

Push or Pull, How Does Silk Flow?

J. Sparkes [1],
[1] University of Sheffield, Sheffield, UK

Silk is one of the longest used and most recognizable textiles that we, as a society, use regularly. We see it as a luxury good, worn as an indicator of success and value. However, despite mankind having domesticated and farmed silkworms for millennia, we still know relatively little about the manufacturing process which converts the liquid silk into the fibers we are so familiar with. Increased ...

Influence of Non-Newtonian Blood Viscosity on Wall Pressure in Right Coronary Arteries with Serial Stenoses

B. Liu [1]
[1] Monmouth University, West Long Branch, NJ, USA

Three dimensional mathematical models are developed to simulate the blood flows in patient specific right coronary arteries with two stenoses. Simulations are carried out with various flow parameters under physiological conditions. Both Newtonian and non-Newtonian blood viscosity models are applied in the simulations to examine the influence of non-Newtonian viscosity of blood on the wall ...