Numerical Investigation of a Time-dependent Magnetic Actuation Technique for Tagging Biomolecules with Magnetic Nanoparticles in a Microfluidic System
A. Munir, J. Wang, Z. Zhu, and H.S. Zhou
Worcester Polytechnic Institute, Worcester, MA, USA
The magnetic body forces that act on mono-dispersed magnetic nanoparticles (MNPs) tagged biomolecules in a microfluidic system can be efficiently used in various applications that involve separation and detection including DNA and protein analysis, bio-defense, drug delivery, and pharmaceutical development. In this work, we report an FEM model to demonstrate a novel method of tagging biomolecules ...
C. Belavý, G. Hulkó, P. Buček, and S. Lel'o
Slovak University of Technology in Bratislava, Bratislava, Slovakia
Technological processes in the engineering practice from point of view of systems and control theory are frequently in the form of distributed parameter systems (DPS). Techniques of FEM based modeling and design of control synthesis methods of DPS which is acceptable for various technological processes, will be demonstrated on modeling and control of temperature fields of the glass melting ...
S. Maloney[1,2], Y. Li[1,2], G. Auner, and J. Smolinski
Wayne State University, Detroit, MI, USA
Lawrence Technological University, Southfield, MI, USA
We are working on a microfabricated lysing chip that uses a piezoelectric actuator to provide ultrasonic energy to break apart cells. The device contains pillars with varying dimensions. We hypothesize that increasing the aspect ratio of pillars will increase the efficiency of the transfer of ultrasonic energy into the fluid phase and enhance the lysing efficiency. The fluid structure ...
S. Lefeuvre, and O. Gomonova
Eurl Creawave, Toulouse, France
Siberian State Aerospace University, Krasnoyarsk, Russia
The microwave heating and processing of heterogeneous material is usually simulated using a set of coupled PDE equations in an homogeneous medium. Nowadays it is possible to describe more accurately the process with a suitable description of the heterogeneities that is at the grain level. Many authors work with spheres (circles) to represent the grains but it is difficult to achieve an ...
L. Murtomäki, and S. Kotha
University of Helsinki, Centre for Drug Research, Helsinki, Finland
Drug therapy of the posterior part of an eye is very challenging. Yet, in USA alone, there are almost 2 million people affected by age related macular degeneration. When designing a strategy for controlled-release drug delivery, it is important to take into account of physiology, absorption, distribution, metabolism, and excretion properties of a drug. Therefore, the aims of this study are: 1) to ...
Homogeneous and Inhomogeneous Model for Flow and Heat Transfer in Porous Materials as High Temperature Solar Air Receivers
O. Smirnova, T. Fend, P. Schwaryboezl, and D. Schoellgen
German Aerospace Center, Institute of Technical Thermodynamics, Koeln, Germany
Results of simulations on flow and heat transfer in a porous Silicon Carbide honeycomb structure applied as a solar air receiver are presented. In this application porous materials are put in concentrated solar radiation. Flux densities of up to 1000 MW/m² are reached. Simultanously, ambient air flows through the material to be heated up to temperatures of app. 800°C. This hot air is then used ...
A. Plana-Fattori[1,2], E. Chantoiseau[1,2], C. Doursat[1,2], and D. Flick[1,2]
AgroParisTech, Massy, France
INRA, Massy, France
Many liquid food processes involve coupled phenomena of fluid flow, heat transfer and product transformation. A typical example is the heat treatment of a starch suspension inside a tubular heat exchanger. Fluid flow influences heat transfer which determines temperature evolution along fluid trajectories. Temperature locally influences the food product transformation. The latter influences ...
V. Di Virgilio, A. Coll, S. Bermejo, and L. Castañer
Universitat Politecnica de Catalunya, Barcelona, Spain
In this work we want to explore some techniques, microfluidic and electrospray-ionization based, suitable for dynamic microarrays\' fabrication. The fabrication techniques are based on manipulation and self-assembly of selective coated micro and nanobeads. The simulation will include electro-osmotic flow, species transport, and electrostatics.
Modeling of Retinal Electrical Stimulation Using a Micro Electrode Array Coupled with the Gouy-Chapman Electrical Double Layer Model to Investigate Stimulation Efficiency
F. Dupont, R. Scapolan, C. Condemine, J.F. Bêche, M. Belleville, and P. Pham
CEA, LETI, Minatec, Grenoble, France
The electrical stimulation for retinal implant has known significant improvements in the last decades with many implantations and experimentations. The ability to create better controlled and adapted signals to increase the efficiency in stimulation is a major objective. The aim of this study is to develop a numerical platform based on COMSOL Multiphysics to simulate different waveforms. The ...
Impact of Velocity and Interfacial Tension on the Performance of Horizontal Wells in Gas Condensate Reservoirs
P. Ghahri, M. Jamiolahmady, and M. Sohrabi
Heriot Watt University, Edinburgh, United Kingdom
Drilling horizontal wells (HWs) has recently received renewed attentions with the increasing trend in exploitation of tight gas reservoirs. An accurate estimation of productivity of such systems using a numerical simulator is a challenging task, because its 3D simulation requires a fine grid exercise to capture the abrupt variation of fluid and flow parameters around the wellbore. This is ...