Effects of Flow and Diffusion on Blood Coagulation in Platelet Poor Plasma: a Two-way Coupling Between Hemodynamics and Biochemistry
D. Magnabosco[1,2], H. van Ooijen, B. Bakker, R. van den Ham
Politecnico di Milano, Milan, Italy
Philips Research, Eindhoven, The Netherlands
Enzyme reactions, blood flow and diffusion in human vasculature play interacting and fundamental roles in blood coagulation. In this complex mechanism, the balance between blood and clot is a delicate equilibrium, whose tight regulation is vital to avoid pathologies such as bleeding and thrombosis. The secondary hemostasis triggered by tissue factor in platelet poor plasma is studied up to ...
B. Castro-Dominguez, R. Ma, A. G. Dixon, Y. H. Ma
Chemical Engineering Department, Worcester Polytechnic Institute, Worcester, MA, USA
The optimization of operating conditions in multitube membrane modules is highly complex. The multiple physics and irregular geometries involved create a challenge for predicting their behavior. This work analyzes the performance of H2 purification through a module containing seven membranes. Using experimental parameters, a 3-D model was devised, specifying the membrane as a reacting boundary ...
K. Cluff, H. Mehraein, B. Jayakumar
Department of Bioengineering, Wichita State University, Wichita, KS, USA
Department of Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA
Background: Peripheral arterial disease (PAD) is characterized by atherosclerotic blockages of the arteries supplying the lower extremities, which cause a progressive accumulation of ischemic injury to the skeletal muscles of the lower limbs. Despite revascularization treatment intervention some PAD patients require follow up secondary treatment due to a continued decline in limb function, ...
A. Warning, A. K. Datta
Department of Biological & Environmental Engineering, Cornell University, Ithaca, NY, USA
Predictive food microbiology currently first requires experimental data for growth on fresh produce and then fitting an empirical or semi-empirical model to the data, making extrapolation to other conditions (temperature, type of produce) difficult. Herein, we develop a mechanistic model for the growth of human pathogenic bacteria (Escherichia coli O157:H7 and Salmonella spp.) on spinach using ...
Numerical Modeling of the Original and Advanced TEMKIN Reactor for Catalysis Experiments in Laboratory Scale - new
D. Götz, M. Kuhn, P. Claus
Ernst-Berl-Institute/Chemical Technology II, Darmstadt, Germany
Many industrial, especially heterogeneously catalysed, processes are characterised by a strong interaction between the reaction kinetics and transport phenomena. Because experiments in laboratory scale can be very time- and cost-intensive, Temkin andKul’kova developed a new reactor design for the direct testing of industrial catalysts. Based on this concept of linearly alternating catalyst and ...
Three-Dimensional Percolation Properties Simulation of a Marine Coating Based on Its Real Structure Obtained from Ptychographic X-Ray Tomography - new
B. Chen, M. Guizar-Sicairos, G. Xiong, L. Shemilt, A. Diaz, J. Nutter, N. Burdet, S. Huo, F. Vergeer, A. Burgess, I. Robinson
London Centre for Nanotechnology, University College London, London, UK
Paul Scherrer Institute, Villigen, Switzerland
AkzoNobel Co. Ltd., Sassenheim, Netherlands
AkzoNobel (UK) Co. Ltd., Tyne and Wear, UK
We present quantitative nano-scale analysis of the 3D spatial structure of an anticorrosive aluminium epoxy barrier marine coating obtained by ptychographic X-ray computed tomography (PXCT) [1-3]. We then use COMSOL Multiphysics® software to perform simulations on the acquired real 3D structure to demonstrate how percolation through this actual 3D structure impedes ion diffusion in the ...
D.Wu, E. Van den Bulck
Katholieke Universiteit Leuven, Department of Mechanical Engineering, KU Leuven, Belgium
Introduction Self-heating behaviour of dust accumulations is a multiphysics field coupled heat and mass transfer in the porous media. A typical experimental apparatus with a hot storage oven and mesh wire baskets has been taken as the study object. The influence of gas flow velocity, oxygen concentration and ambient temperature on the self-heating behaviour of the dry coal dust sample has been ...
Microscale Simulations of Catalyst Deactivation During Gas-Phase Upgrading of Biomass Pyrolysis Vapors
P. N. Ciesielski , D. Robichaud , B. Donohoe , M. Nimlos ,
 Biosciences Center, National Renewable Energy Laboratory, Golden, CO, USA
 National Bioenergy Center, National Renewable Energy Laboratory, Golden, CO, USA
Catalytic fast pyrolysis is a process by which biomass may be converted into liquid hydrocarbon transportation fuels and chemical co-products that are alternative to their petroleum-derived counterparts. Chemical compounds in raw pyrolysis vapor have high oxygen content and therefore must be deoxygenated in order to meet specifications for hydrocarbon fuels. One strategy to accomplish this is ...
Using COMSOL Multiphysics to Model Crust Development at the Surface of Whole Beef Meat Subjected to Hot Air Jet
J. Sicard , S. Portanguen , C. Chevarin , A. Kondjoyan 
 INRA Auvergne-Rhône-Alpes, Saint-Genès-Champanelle, FRANCE
Crust which develops at the surface of meat leads to reactions which affect food color, flavor and safety. Whole pieces of meat are only contaminated by microorganisms at their surface. Thus intense thermal treatment can inactivate pathogenic bacteria; however the associated high temperatures also lead to the formation of carcinogenic compounds. An experimental study of crust development at ...
R. Busqué , R. Torres , A. Husar , J. Grau 
 Escola Universitària d'Enginyeria Tècnica Industrial de Barcelona, Barcelona, Spain
 Institut de Robòtica i Informàtica Industrial CSIC-UPC, Barcelona, Spain
The storage of hydrogen as an absorbed element in metal hydride bottles is a promising technique for energy storage. In this work, a three-dimensional model of a charging process in a metal hydride container has been developed to simulate the absorption reaction and resultant heat and mass transport phenomena in metal hydride vessels. The model has been experimentally validated showing a good ...