Technical Papers and Presentations

Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Numerical Simulation of Magnetic Drug Targeting with Flow – Structural Interaction in an Arterial Branching Region of Interest

A. Morega, A. Dobre, and M. Morega
University Politehnica of Bucharest, Bucharest, Romania

We report a numerical study on the blood – magnetic carrier aggregate flow in an external magnetic field, for applications such as magnetic drug targeting. The arterial system morphology is complex and patient-related therefore more realistic numerical simulations request medical image-based reconstruction to generate computational domains. Simpleware package is used to generate the ...

Bone Remodeling Following Total Hip Replacement: Short Stem Versus Long Stem Implants

M.S. Yeoman[1], A. Cizinauskas[1], C. Lowry[2], G. Vincent[3], S. Collins[3], D. Simpson[3]
[1]Continuum Blue, Tredomen, Ystrad Mynach, United Kingdom
[2]Corin Group, Cirencester, United Kingdom
[3]Imoprhics, Manchester, United Kingdom

Bone resorption around hip stems, in particular periprosthetic bone loss, is a common observation post-operatively. A number of factors influence the amount of bone loss over time and the mechanical environment following total hip replacement (THR) is important. Conventional long stem prostheses have been shown to transfer loads distally, resulting in bone loss of the proximal femur. More ...

Wireless Power and Communications for Implantable Biosensors

C. Romero[1], M. Mujeeb-U-Rahman[1]
[1]California Institute of Technology, Pasadena, CA, USA

Implantable biosensors have the potential to revolutionize the healthcare industry by allowing patients and their health care providers to continuously monitor blood pH levels, pCO2, proteins, metabolites, and a wide variety of other biomolecules. These devices need to operate completely wirelessly to be used for long term monitoring. Metal coils are attractive candidates for wireless power ...

Modeling of Nerve Stimulation Thresholds and Their Dependence on Electrical Impedance with COMSOL

P. Krastev[1], and B. Tracey[1]
[1]Neurometrix, Inc., Waltham, Massachusetts, USA

Nerve localization is important for applications in regional anesthesia. Localization is achieved by stimulating the nerve with an electric field produced by a current from a needle inserted into the body of the patient, close to the target nerve.  Modeling of the electric field in close proximity to the nerve may help to explain observed variations in threshold currents and can help to ...

Compensating Spatial Variability of Quantity Index in 2D Electrical Impedance Tomography: COMSOL Multiphysics Study

S. Oh, and R. Sadleir
Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA

In Electrical Impedance Tomography (EIT), an array of surface electrodes is used to inject current and measure the resulting voltages to non-invasively obtain conductivity distributions of objects. The system can be easily implemented as a device that monitors hemorrhage, respiration, gastric emptying or brain activities.The Quantity Index (QI), an integral measure of reconstructed images, can be ...

Dynamic Simulation Of Particle Self-Assembly Applied To Microarray Technology

V. Di Virgilio, A. Coll, S. Bermejo, and L. Castañer
Universitat Politecnica de Catalunya, Barcelona, Spain

In this work we want to explore some techniques, microfluidic and electrospray-ionization based, suitable for dynamic microarrays\' fabrication. The fabrication techniques are based on manipulation and self-assembly of selective coated micro and nanobeads. The simulation will include electro-osmotic flow, species transport, and electrostatics.

Influence of pH and Carbonate Buffering on the Performance of a Lactate Microbial Fuel Cell

A.Torrents, N. Godino, F.J. del Campo, F.X. Muñoz, and J. Mas
Universitat Autònoma de Barcelona, Spain

Microbia Fuel Cells (MFC’s) are complex environments where electrochemical, physical and biological aspects must be considered together. In this work we present a 1D model partially describing a Shewanella oneidensis MFC that degrade sodium lactate [lactate -> Acetate + CO2 + 2H+ + 2e-]. The model, simulated using COMSOL, focuses on pH implications of the MFC operation. Release of protons ...

Numerical Homogenization in Multi-scale Models of Musculoskeletal Mineralized Tissues

A. Gerisch[1], S. Tiburtius[1], Q. Grimal[2], and K. Raum[3]
[1]Technische Universität Darmstadt, Darmstadt, Germany
[2]Laboratoire d’Imagerie Paramétrique, UPMC, Paris, France
[3]Julius Wolff Institut & Berlin-Brandenburg School for Regenerative Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany

Musculoskeletal mineralized tissues (MMTs), e.g. bone, are hierarchical composite materials. Their effective elastic properties at different scales are of interest for computational studies of the MMT’s response to mechanical loading but also to realistically simulate implant osseointegration. We combine multi-scale and multi-modal experimental techniques with mathematical modelling of MMTs ...

Photon Migration Through Multiple Layers of Biological Tissue

M.S. Yeoman[1], E. Sultan[2]
[1]Continuum Blue, Tredomen, Ystrad Mynach, United Kingdom
[2]College of Technological Studies, PAAET, Adailiyah, Kuwait

The modeling of light propagation through multiple layers of biological tissue are assessed & compared to the theoretical predictions by Perelman at al. [94 & 95] of the most-favorable-path (MFP). The MFP on which photons will be found can be obtained from the path of the net flux propagation using the diffusion equation. The diffusion equation is valid when studying diffuse light propagation, ...

Simulating Thermotherapeutic Response Induced by Thermal Padding for Treating Acute Injuries

J. Kantor[1], Y. Feng[1], C. Acosta[1], E. Massingill[1]
[1]University of Texas at San Antonio, San Antonio, TX, USA

Cryotherapy and thermotherapy are common methods of treatment for acute injuries ranging from ankle sprains to complex surgery. The idea behind such treatment is that a change in temperature will reduce pain and constrict fluctuations in blood flow at the targeted area. The purpose of this study is to simulate the vascularized tissue reaction and the resulting blood flow fluctuation from thermal ...

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