See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.


View the COMSOL Conference 2023 Collection

Bioscience and Bioengineeringx

Modelling swellable Microneedles for transdermal drug delivery

Prateek Ranjan Yadav1, Diganta Bhusan Das1, Sudip Pattanayek2
1Loughborough University, Loughborough, UK
2Indian Institute of Technology Delhi, New Delhi, India

Swellable microneedles (SMN) have gained a lot of attention to the transport of drugs in the skin. Microneedle swells by absorbing interstitial fluid, causing the loaded drug to transport into the skin without polymer dissolution which reduces the chance of infection and skin irritation. ... Read More

Numerical Simulations for Designing Wireless Electrochemiluminescence Imaging Microdevices

Pascale PHAM1, Abdulghani Ismail2, Silvia Voci3, Loïc Leroy2, Ali Maziz4, Lucie Descamps2, Alexander Kuhn3, Pascal Mailley1, Thierry Livache2, Arnaud Buhot2
1CEA-LETI, Minatec Campus, Grenoble, France
2Univ. Grenoble Alpes, CEA, CNRS, INAC-SyMMES, 38000 Grenoble, France
3Univ. Bordeaux, CNRS, Bordeaux INP, ISM, UMR 5255, F-33400, Talence, France
4LAAS-CNRS, Université de Toulouse, 31400 Toulouse, France

ElectroChemiLuminescence (ECL) is a phenomenon of light emission resulting from an initial electrochemical reaction [1]. Today, ECL is used for detecting biomolecules (DNA, RNA, biomarkers). Unlike other optical detection methods used in biosensors (e.g. fluorescence), ECL is a highly ... Read More

Modelling of an Innovative Directional Ultrasonic Atherosclerosis Treatment Device

J.-D. Wheeler1, V. Bruyere1, N. Aeby2
1SIMTEC, Grenoble, France
2Designer

Atherosclerosis prevalence keeps increasing worldwide because of the sedentary lifestyle and aging of the population. It is a pathology which is characterized by the build-up of plaque on the artery walls. While it has no incidence at the beginning, the blood flow can be severely altered ... Read More

Concentration polarization effects in a single pass membrane module for continuous diafiltration

Ruijie Tan1, Matthias Franzreb1
1Karlsruhe Institute of Technology, Karlsruhe, Baden Württemberg, Germany

Concentration polarization (CP) is a common problem in membrane filtration. It is caused by the convective transport of large molecules towards the membrane surface, however while the solvent passes the membrane as permeate, the molecules are retained and accumulate at the membrane ... Read More

Patient-specific Analysis of Left Ventricle Motion

I. J. Colorado-Cervantes1, L. Teresi2, V. Sansalone1
1Univ Paris Est Creteil, France
2University Roma Tre, Rome, Italy

We present a framework for patient-specific study of cardiac motion; in particular, we focus on the deformations of a beating Left Ventricle (LV), confronting numerical simulations with real data acquired by echo-cardiography. Our goal is to determine the clinical importance of the LV ... Read More

Cristalline Lens abberration during Laser Surgery

A. Maurer1, J. Minardi2, R. Rozsnyo2, D. Enfrun1, R. Boulandet2
1Kejako SA, Switzerland
2HEPIA, University of Applied Sciences Western Switzerland

Femtosecond laser are now a regular tool of the modern ophtalmic surgeon, for instance in cataract surgery by enabling precise cut of the cristalline lens tissue before removal. As femtosecond laser tissue interaction is highly dependant of the energy spatial density, a simplified model ... Read More

Geometric exploration and optimisation of porous ceramic reactors for bioethanol production

Joe Alexandersen1, Jeffrey Gerard 2
1University of Southern Denmark, Denmark
2Ecole Polytechnique Universitaire de Montpellier, Montpellier, France

This work investigates the design of porous ceramic reactors for continuous bioethanol production through simulations using COMSOL Multiphysics®. Porous ceramic structures will be seeded with the yeast Saccharomyces cerevisiae and exposed to a continuous flow of glucose solution, from ... Read More

COMSOL® Experience Of Biomechanical Modeling Of Shells And Plates In Ophthalmology

Pavilaynen G. V.1, Franus D.V.2
1Saint-Petersburg State University, Russia
2

Modern problems of biomechanics, in particular, the problems of modeling vision correction in ophthalmology are associated with the study of the stress-strain state of shells and plates made of complex materials. These problems are essentially nonlinear in geometry and in physical ... Read More

Numerical Model of Induced Transmembrane Voltage for Cell Electroporation Using COMSOL Multiphysics®

U. Ghosh1, J. D. Zahn1
1Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey, USA

Electroporation is the process of creating temporary hydrophilic pores in the cell membrane by applying an external electric field of specific strength and duration. It is used for gene transfection, and transport of other useful biomolecules and therapeutic drugs into the cell. When a ... Read More

Investigating the Impact of Substrate Composition on 3D Printed mmWave CSRR Sensor

J. Persad1, S. Rocke1, A. Roopnarine1, A. Abdool1
1Department of Electrical & Computer Engineering, The University of The West Indies, Trinidad & Tobago

Diabetes is a chronic noncommunicable disease which lays a heavy burden on many impoverished communities globally. The ability to monitor and manage the disease is one key component to lessening its impact. 3D printing (3DP) offers an economical manufacturing method to produce medical ... Read More